Winter indoor air pollution to prevent leukemia
With the advent of winter, the doors and windows are mostly closed indoors instead of offices or homes. Over time, the indoor air will become dirty, which will easily bring diseases to the body.
With the increasingly serious environmental pollution, the relationship between environmental exposure and childhood leukemia has caused widespread concern.
Indoor air is one of the fastest and closest external environments that people come in contact with. About 70% of people?
90% of the time is spent indoors, and more than the exposure to indoor air pollution, especially children, the long-term indoor air quality is expected to become more and more important.
Leukemia accounts for the largest proportion of children’s tumors, with the highest mortality rate. Epidemiological studies of complications have shown that the incidence of leukemia is on the rise. Prevention and treatment of childhood leukemia are the focus and focus of leukemia research.
The specific cause of childhood leukemia is now apparent.
Most are thought to be the result of a combination of factors (individual susceptibility and external environment).
Indoor air pollution may play a more important role in the development of childhood leukemia.
1 Smoking control Smoking is a public health problem that needs to be solved urgently, and the harm caused by passive smoking is particularly serious.
A large number of studies have confirmed that smoking is the initial result of lung cancer. In addition to high blood pressure, it can cause many types of cancer.
According to the WHO report, there are 44 “definite carcinogens” in tobacco smoke.
Parental smoking increases the risk of developing leukemia by 50%, adversely affects the prognosis of acute myeloid leukemia (AML), and shortens survival.
Maternal heavy smoking (≥10 sticks / day) can increase the risk of AML in children, with the highest hazard ratio reachable2.
2 Benzene and other organic solvents Benzene is a slightly aromatic organic solvent that has a wide range of uses in industry.
The source of indoor benzene pollution is mainly volatile organic compounds released from air pollution into the interior and interior decoration materials.
Once the interior is renovated, they are always released into the indoor air from the decoration materials.
If the indoor population is over-exposed to typical polluted air, human health will be damaged to varying degrees.
Long-term exposure to low concentrations of benzene can lead to chronic benzene poisoning, aplastic anemia, myelodysplastic syndromes and even leukemia.
Studies on the relationship between occupational benzene exposure and adult leukemia have obtained positive evidence. Workers exposed to benzene concentrations of 67 mg / m3 per year are 20 times more likely to develop AML than the general population. Benzene workers have a higher incidence of acute lymphoblastic leukemia (ALL)To other people.
There is still research on the relationship between adolescent and child leukemia and direct benzene exposure, but the increasing benzene concentration in indoor air may be one of the causes of childhood leukemia.
Studies by British scholars have found that children living within 100 meters of major traffic lanes or gas stations have higher concentrations of benzene and other hydrocarbons than children in other places, and the risk of leukemia in children is slightly higher than in other areas. AML, ALLCLL is significantly related to the number of cars owned by households, and benzene exposure in gasoline may be the reason.
Childhood leukemia is related to factories near the house, which are two major industrial atmospheric emissions-oil volatiles and smoke from boilers or internal combustion engines that increase their risk.
In some places with severe air pollution, there are many children with leukemia.
The survey found that 90% of families with children with leukemia had been renovated within 6 months to 1 year, and most of them had used luxury stone and stylish decoration materials.
If mothers are exposed to solvents, paints, substitutes, and cosmetic agents before and during pregnancy, father’s exposure to cosmetic agents before marriage increases the risk of children developing ALL and has a time-effect relationship.
Children’s frequent exposure (more than 4 times / month) to organic solvents will increase the risk of all diseases, and found that the mother lived in a painted room one year before the child’s birth, and the child’s risk of ALL after birth was also increased, so children with ALLThe increased risk is associated with certain indoor activities and paint exposure in children’s homes after birth.
3 Household chemicals Household chemicals refer to chemical products used in the daily and residential environment of the home.
Household chemicals are widely used, penetrating into people’s clothing, food, housing, and travel, and covering all aspects of life. Therefore, household chemical reagents have scattered uses, large demand, and a wide range of coverage (including multiple ages)Paragraph) and long exposure time.
Various household chemicals can enter the human body through different ways and cause harm to health due to their different purposes, methods and scopes.
Children’s exposure to household chemicals varies greatly depending on the region and the home environment in which pesticides and hair dyes are closely related to childhood leukemia.
Multiple studies have shown that pesticides are linked to leukemia.
Occupational or home exposure to pesticides is highly correlated with leukemia, especially childhood AML.
Children whose fathers have a history of exposure have increased susceptibility, and children are more at risk of direct exposure to pesticides than adults.
The more types of pesticides used in the home, the higher the frequency and the likelihood of suffering from ALL.